Produced by disciples of the Ramtha School of Englightenment, "WHAT THE BLEEP DO WE KNOW?!" is nothing like conventional films. Eeverything in it is alive, and reality is changed by every thought. Thus it forces viewers to a higher plane of consciousness, worthy of Einstein or Copernicus. Both a documentary and a story, its mind-blowing special effects plummet the viewer into a world in which reality takes on quantum uncertainty, and where the protagonist experiences her own neurological processes and perceptual shifts.

Amanda (Matlin), a divorced photographer, finds herself in a fantastic wonderland when her daily, uninspired life falls apart, revealing quantum worlds within worlds. Guided by a Greek Chorus of leading scientists and mystics, she finds that either reality is very questionable or that Amanda's view of it should be. Suddenly, everything is alive, and reality is changed by every thought, as posed by modern radical souls of science, who are the true heroes, as they conquer and map the greatest uncharted territory yet - human consciousness.